Eggs are a staple in many diets, packed with protein, vitamins, and essential nutrients. However, for individuals with autoimmune diseases, eggs may not always be the best choice. Some people find that eggs trigger inflammation, contribute to leaky gut, or exacerbate autoimmune flares. But is this true for everyone?

This blog explores whether eggs are bad for autoimmune disease, how they affect inflammation, and whether they should be eliminated from an autoimmune-friendly diet plan.
Understanding Autoimmune Disease and Diet
Autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues. Conditions like Hashimoto’s disease, rheumatoid arthritis, lupus, and multiple sclerosis are all forms of autoimmune disorders. While genetics play a role, diet has a significant impact on symptom management.
Many experts recommend an anti-inflammatory diet that removes potential triggers, including inflammatory foods and autoimmune conditions. This is why the autoimmune protocol (AIP) diet exists—it helps identify problematic foods that may worsen symptoms.
Are Eggs Inflammatory for Autoimmune Disease?
One major concern about eggs is their potential to cause inflammation. Inflammation is the body’s natural defense mechanism, but in autoimmune disorders, the immune system is already overactive. If eggs contribute to inflammation, they could worsen symptoms.
Why Eggs Might Be Problematic for Autoimmune Conditions
Egg Whites Contain Proteins That May Trigger Immune Reactions
Egg whites contain lysozyme, an enzyme that can contribute to leaky gut and autoimmune diseases by increasing gut permeability.
The proteins in egg whites, such as ovalbumin, can trigger immune responses in sensitive individuals.
Egg Yolks Are High in Arachidonic Acid
While egg yolks are rich in nutrients, they also contain arachidonic acid, which is linked to inflammation.
If your body struggles with chronic inflammation, consuming foods high in arachidonic acid may worsen symptoms.
Egg Allergy vs. Autoimmune Response
Some individuals have a true egg allergy, which is different from an autoimmune reaction.
Egg intolerance in autoimmune disorders may not be a full allergy but can still contribute to symptoms like bloating, fatigue, and joint pain.
AIP Diet and Egg Elimination
The autoimmune protocol (AIP) diet is designed to reduce inflammation and heal the gut by eliminating potential triggers. Eggs are excluded from the AIP diet because of their potential to cause inflammation and contribute to leaky gut.
Should You Remove Eggs from Your Diet?
If you have an autoimmune disease like Hashimoto’s, lupus, or Crohn’s, you may benefit from an AIP diet and egg elimination for a few weeks.
After the elimination phase, you can try reintroducing eggs and observe whether symptoms return.
Do Eggs Cause Leaky Gut?
A compromised gut lining is often linked to autoimmune diseases. Leaky gut syndrome occurs when the intestinal barrier becomes permeable, allowing toxins and undigested food particles to enter the bloodstream.
How Eggs May Contribute to Leaky Gut
- Egg whites contain protease inhibitors, which can be difficult to digest.
- Lysozyme in egg whites binds to bacteria in the gut, potentially affecting gut health.
- For individuals with an already weakened gut barrier, consuming eggs regularly may increase intestinal permeability, worsening autoimmune symptoms.
If you’re dealing with leaky gut and autoimmune diseases, removing eggs might be beneficial during the healing process.
Are Eggs Bad for Hashimoto’s Disease?
Hashimoto’s disease is an autoimmune thyroid condition that affects metabolism, energy levels, and overall well-being. Eggs may not be suitable for some individuals with Hashimoto’s because:
- The proteins in egg whites can be difficult for those with thyroid issues to digest.
- Egg yolks contain iodine, which is essential for thyroid function but may trigger symptoms in some individuals.
- Some people with Hashimoto’s also have food sensitivities that make eggs problematic.
Can Eggs Trigger Autoimmune Flares?
An autoimmune flare happens when symptoms suddenly worsen. Common triggers include stress, infections, and diet. Since eggs are inflammatory for autoimmune disease in some cases, they might contribute to flare-ups.
Signs That Eggs Might Be a Trigger for You
Increased joint pain or stiffness
Digestive issues like bloating or diarrhea
Skin flare-ups (eczema, psoriasis, or acne)
Increased brain fog or fatigue
If you notice any of these symptoms after consuming eggs, consider eliminating them and switching to anti-inflammatory breakfast options for autoimmune sufferers.
Best Egg Substitutes for Autoimmune Diet
If you need to replace eggs in your diet, here are some great alternatives:
For Baking:
- Flaxseed or chia egg (1 tbsp ground flaxseed + 3 tbsp water = 1 egg)
- Mashed banana (¼ cup per egg)
- Unsweetened applesauce (¼ cup per egg)
For Cooking:
- Scrambled tofu (great for replacing scrambled eggs)
- Coconut yogurt (for texture in recipes)
How to Test for Egg Sensitivity in Autoimmune Disease
Not everyone with an autoimmune condition needs to avoid eggs. Here’s how you can test for sensitivity:
Try an Elimination Diet
Remove eggs for 30 days, then slowly reintroduce them while monitoring symptoms.
Use a Food Journal
Track how you feel after eating eggs to identify any patterns.
Consider Lab Testing
Some food sensitivity tests can detect an immune response to eggs.
If you suspect eggs trigger autoimmune flares, consult with a healthcare provider or a nutritionist to determine the best dietary approach for you.
Final Thoughts
The answer depends on your body’s response. While eggs are nutrient-dense, they can be inflammatory for autoimmune disease in certain individuals.
Key Takeaways:
If you experience worsening autoimmune symptoms after eating eggs, consider removing them.
Egg whites contain proteins that may contribute to leaky gut and inflammation.
Egg yolks contain arachidonic acid, which could increase inflammation in some people.
Try eliminating eggs for 30 days and monitor your symptoms.
If you tolerate eggs well, you may be able to include them in moderation.
For those looking for autoimmune-friendly breakfast options, replacing eggs with flax eggs, chia eggs, or scrambled tofu can be a great alternative.
If you’re unsure whether eggs are bad for autoimmune disease, start by experimenting with an elimination diet and listen to your body’s signals.